What Are the Skin Changes Associated with Breast Cancer?

July 2, 2024
What Are the Skin Changes Associated with Breast Cancer?

When it comes to breast cancer, your skin can reveal a lot about what's happening beneath the surface. Recognizing these changes early can make a significant difference in your diagnosis and treatment. Below, we share the most common skin changes associated with breast cancer.

Skin Changes You Should Look Out For

Here are the skin changes you should be on the lookout for.

Redness and Swelling

One of the earliest signs you might notice is redness or swelling in your breast. This isn't the kind of redness that comes from a sunburn or an irritation. Instead, it can appear almost like an infection, with the skin looking inflamed and feeling warm to the touch. According to studies, inflammatory breast cancer (IBC) often presents with these symptoms. It's a rare but aggressive form of breast cancer, so if you notice persistent redness and swelling that doesn't go away, it's crucial to consult your doctor.

Skin Dimpling or Puckering

Another key sign is dimpling or puckering of the skin. This change can make your breast skin look like an orange peel – a condition known as "peau d’orange." This texture occurs because the cancerous cells block the lymphatic vessels in the skin, causing fluid build-up and tightening of the skin. The American Cancer Society emphasizes that this kind of skin change is significant and should prompt immediate medical evaluation.

Changes in Skin Texture

You might also observe changes in the texture of the skin on your breast. This can include areas that feel thicker or rougher than the surrounding skin. Sometimes, these areas can feel similar to scar tissue or might be hard to the touch. Studies indicate that these changes occur as the cancer grows and the cells infiltrate the skin, causing it to thicken and lose its elasticity. If you notice any areas on your breast that feel different in texture, it's important to get them checked out.

Itchiness and Rash

Breast cancer can sometimes cause itchiness or a rash on the skin of your breast. While it’s easy to dismiss these symptoms as a minor skin condition, persistent itchiness or a rash that doesn’t respond to usual treatments should be taken seriously. Research notes that itchiness and rashes can be early indicators of Paget’s disease of the breast, a rare type of cancer that starts on the nipple and extends to the areola.

Nipple Changes

Pay close attention to any changes in your nipple. This can include inversion, retraction, or flattening of the nipple, where it turns inward or changes position. Additionally, if you experience unusual nipple discharge, especially if it's bloody or clear (and not related to breastfeeding), this can be a warning sign.

Ulceration and Open Sores

In more advanced cases, you might see ulceration or open sores on your breast. These sores can be painful and might not heal easily. They occur when the skin breaks down due to the underlying tumor growing and pushing through the skin.

Inflammatory Breast Cancer (IBC)

Inflammatory breast cancer (IBC) is one of the more aggressive and fast-growing forms of breast cancer. Although it is rare, accounting for only about 1-5% of all breast cancer cases according to the American Cancer Society, it is critical to recognize its symptoms early due to its rapid progression.

IBC often presents differently than more common types of breast cancer. Instead of a distinct lump, IBC typically causes the breast to become red, swollen, and warm. This redness can cover a third or more of your breast, giving it an inflamed appearance similar to an infection. The warmth and swelling are due to cancer cells blocking the lymphatic vessels in the skin. This blockage leads to fluid buildup and results in the distinctive symptoms.

One of the hallmark signs of IBC is a change in the texture of the skin on your breast (peau d’orange), as we discussed earlier. You might also notice that your breast feels heavy, hard, or tender. These sensations are due to the rapid growth of cancer cells, which can cause the breast to swell significantly. This is because unlike other forms of breast cancer that develop slowly over months or years, IBC can progress within weeks.

Nipple changes are another critical symptom of IBC. The nipple may become flattened, inverted, or develop a rash that doesn’t heal. There can also be discharge from the nipple, which is typically clear or bloody. These changes occur because the cancer affects the ducts behind the nipple and alters its appearance and function.

Diagnostic Approaches for Skin Changes

When you notice any unusual skin changes on your breast, it’s important to seek medical advice promptly. Diagnosing the underlying cause of these changes involves several steps, including clinical examinations, imaging tests, and biopsies. The first step in diagnosing skin changes associated with breast cancer is a thorough clinical examination. During this exam, your doctor will carefully inspect the affected breast, noting any redness, swelling, dimpling, or other abnormalities. They will also feel for lumps or areas of thickened tissue. It's crucial to describe any symptoms you've noticed, such as itchiness, pain, or discharge. Your medical history and any family history of breast cancer will also be discussed, as these factors can influence the likelihood of a cancer diagnosis.

Self-examination plays a vital role as well. For instance, regularly checking your breasts can help you become familiar with their normal appearance and texture, making it easier to spot any changes early. According to the National Breast Cancer Foundation, self-exams should be done monthly, ideally at the same time each month. If you find any unusual changes, report them to your healthcare provider immediately.

Imaging tests are the next step in the diagnostic process. Mammography is the most common imaging technique used to examine breast tissue. This X-ray can detect tumors and other abnormalities that might not be palpable. However, for inflammatory breast cancer (IBC) and other conditions that cause diffuse changes rather than distinct lumps, mammograms might not always be conclusive.

In such cases, an ultrasound might be used. Ultrasound can help differentiate between solid masses and fluid-filled cysts, which can provide additional information about the nature of the abnormality. Your doctor may also recommend magnetic resonance imaging (MRI). An MRI uses magnetic fields and radio waves to create detailed pictures of the breast tissue and is particularly useful for evaluating the extent of cancer.

A definite diagnosis can also often require a biopsy. During a biopsy, a sample of tissue from the suspicious area is taken and examined under a microscope. There are several types of biopsies that might be performed:

  • Fine Needle Aspiration (FNA): This involves using a thin, hollow needle to withdraw a small amount of tissue or fluid from the lump or affected area. It's a quick procedure that can provide immediate results.
  • Core Needle Biopsy: This method uses a larger needle to remove a small cylinder of tissue from the abnormal area. It's more comprehensive than FNA and can provide more detailed information.
  • Surgical Biopsy: If the results from FNA or core needle biopsy are inconclusive, a surgical biopsy may be performed. This involves removing a larger portion of tissue for examination and is typically done under local or general anesthesia.

It’s also worth noting that new diagnostic techniques are continuously being developed. Advances in molecular imaging and genetic testing are providing more precise tools for diagnosing breast cancer. Genetic testing, for example, can identify mutations in genes like BRCA1 and BRCA2, which significantly increase the risk of breast cancer.

Throughout the diagnostic process, communication with your healthcare team is key. Don't hesitate to ask questions about the tests being performed, what the results mean, and the next steps.

Treatment Options

When it comes to treating breast cancer that presents with skin changes, a multi-faceted approach is often necessary. These skin changes, such as redness, swelling, or dimpling, can indicate more aggressive or advanced forms of breast cancer, which require a comprehensive treatment plan.

One of the primary treatment options for breast cancer with skin changes is surgery. Surgery aims to remove the cancerous tissue from the breast. There are several types of surgeries, each tailored to the extent of the disease. A lumpectomy involves removing the tumor and a small margin of surrounding tissue, preserving most of the breast. In more advanced cases, a mastectomy, which entails removing the entire breast, might be necessary.

At times, radiation therapy is also used in conjunction with surgery to eliminate any remaining cancer cells. This treatment uses high-energy rays to target and kill cancer cells. This type of treatment is particularly crucial for skin changes associated with inflammatory breast cancer (IBC) because it can address cancer cells that have spread to the skin and lymphatic vessels.

Chemotherapy is another commonly known form of breast cancer treatment, especially for cancers that have spread beyond the breast or are aggressive in nature. Chemotherapy uses drugs to destroy cancer cells throughout the body. In cases of IBC or other advanced breast cancers, neoadjuvant chemotherapy (administered before surgery) can shrink tumors, making them easier to remove surgically. This approach has been shown to improve surgical outcomes and overall survival rates.

Hormone therapy may be used if your cancer is hormone receptor-positive, meaning the cancer cells grow in response to hormones like estrogen or progesterone. Drugs such as tamoxifen or aromatase inhibitors can block these hormones and help slow or stop the growth of cancer. Apart from this, there is targeted therapy that involves drugs that specifically target cancer cells while sparing normal cells, leading to fewer side effects compared to traditional chemotherapy.

Managing the side effects of cancer and treatment on your skin is also crucial for maintaining your overall well-being. For instance, it is recommended to keep your skin clean and moisturized helps to prevent dryness and irritation, which are common issues during cancer treatment. Your healthcare team might suggest specific creams or ointments to soothe your skin. We also recommend, avoiding harsh soaps and hot water since they can cause irritation.

In some cases, medications for skin symptoms might be necessary. Topical corticosteroids can help reduce inflammation and itching, while antibiotics might be needed if there is a secondary infection. If you experience severe skin reactions, your oncologist may adjust your treatment plan to balance effectiveness with quality of life.

Overall, the treatment for breast cancer with skin changes is highly personalized, taking into account the type, stage, and specific characteristics of your cancer. As a patient, it is important for you to stay informed and actively participate in your treatment planning with your healthcare team. It can significantly impact your journey. The advances in medical research continue to improve the outlook for breast cancer patients, which provides hope and better outcomes for those affected.

At BASS Cancer Center, we understand that early detection and comprehensive treatment are key to fighting breast cancer effectively. Our dedicated team of specialists is committed to providing you with the highest standard of care, personalized to meet your unique needs. If you’ve noticed any unusual skin changes or other symptoms, don’t wait. Schedule a consultation with our expert oncologists today. Let us help you navigate this journey with the best medical support and compassionate care.